What is LiV?

What is Low-intensity Vibration (LiV)?

The potential for Low-intensity Vibration (LiV) therapy to treat osteoporosis was established by Prof. Dr. Clinton Rubin, one of the world’s foremost biomedical engineers. in the 1980s.

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By stimulating the body’s stem cells – specifically, those in the legs – Marodyne LiV encourages bone growth and maintains bone health. It’s helping people with osteoporosis do the things they love for longer.

Marodyne LiV sends out signals that correspond to the natural, mechanical movement impulses that are are picked up by the skeleton every step we take. The frequency is calibrated precisely to accurately mimc the forces that our bones are exposed to while walking or undertaking gentle activity.

The device stimulates osteoblast (bone-building) activity while inhibiting osteoclast (bone wasting) activity. Studies have established that just 10 minutes of LiV a day can help to keep bones strong and healthy. 

The device automatically calculates your weight and delivers the right amount of vibration for you. Preventing osteoporosis and improving bone health just got simpler.

Learn more about how Marodyne works below.

Marodyne LiV provides an exact low-level vibration (0.4g) transmitted at a high frequency (30Hz) to the person standing on the device.

An impulse of 0.4 g is applied to the base (sole of the foot), approx. 0.1 g is damped in the leg area and 0.3 g is passed on to the hip and spine (‚g‘ stands for gravity – our acceleration due to gravity with ~ 9.81 m/s²).A primary effect of the signals (impulses or dynamic force peaks) between muscle tissue and bone is the stimulation of mesenchymal stem cells (MSC).

These stem cells have the potential to develop into a multitude of cells including bone, cartilage and fat cells. If they are encouraged to form bone, then they can compensate for the cell loss caused by osteoporosis and other conditions.

The Low-intensity Vibrations emitted by Marodyne LiV imitate the stronger signals (of a younger body), replicating the behaviour of a healthy muscle structure to reduce the build-up of fat cells and activate the production of bone cells. It achieves this by stimulating the bone-forming processes within the mesenchymal stem cells.

Over time, Marodyne LiV can reduce – and in some cases halt – the degradation of bone mass. In time, it can help to build a healthy musculoskeletal system, counteracting the damage done by osteoporosis and other bone-damaging conditions.

Our knowledge about the role of mechanical signals and their effect on the human body has improved over the last 25 years through vibration research, funded by NASA, Universities, and various government agencies.

There are hundreds of studies establishing the benefits of Low-intensity Vibration, including a recent Nature review that concluded: “Empirical evidence suggests that mechanical signals can be used to prevent and/or treat osteoporosis and obesity.”

You can learn more about the science behind Marodyne LiV by reading our in-depth whitepapers.

Several decades of research have shown that low-intensity vibration is a safe alternative to current drug treatments.

Through LiV, bone is grown, muscles are stimulated, circulation is increased and balance and mobility are improved.

To achieve the optimum benefit of this natural therapy, scientists agree that Marodyne LiV needs to be used for at least 10 minutes every day.

“I have spent the last 30 years of my life trying to understand how mechanical signals modulate bone, bone mass, and morphology. The low-intensity vibration frequency has the capacity to dictate the regeneration patterns of Mesenchymal Stem Cells (MSCs) found within the body to stimulate bone and muscle. “We have discovered, through our many years of scientific research, that Low-intensity Vibration can fight against diseases such as obesity and diabetes. Scientific research has also shown that low-intensity vibration frequencies can reduce bone loss in individuals with osteoporosis, osteopenia, or sarcopenia.”
Dr. Clinton Rubin
Distinguished Professor, Chair of Department of Biomedical Engineering, Director of Center for Biotechnology, Stony Brook University